Found 10 matching trials
Efficacy, Safety and Tolerability of ISIS 304801 in People With Partial Lipodystrophy With an Open-Label Extension PHASE2 Background:
Partial lipodystrophy is a deficiency of body fat in parts of ...
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National Institutes of Health Clinical Center, 9000 Rockville Pike
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The APPROACH Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Patients With Familial Chylomicronemia Syndrome PHASE3 The purpose of this study is to evaluate the efficacy and safety of volanes...
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IONIS Investigative Site
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The COMPASS Study: A Study of Volanesorsen (Formally ISIS-APOCIIIRx) in Patients With Hypertriglyceridemia PHASE3 The purpose of this study is to evaluate the efficacy and safety of volanes...
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IONIS Investigative Site
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Volanesorsen Early Access Program for Patients With Familial Chylomicronemia Syndrome (FCS) N/A The purpose of this program is to provide expanded access to volanesorsen f...
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No Longer Available
Location
Multiple Locations
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Mechanistic Study of ISIS ISIS-APOCIIIRX in Type 2 Diabetes PHASE2 The purpose of this study is to evaluate the effects of ISIS ISIS-APOCIIIRX...
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Profil Institute for Clinical Research
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The BROADEN Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants With Familial Partial Lipodystrophy PHASE2 The purpose of this study is to evaluate the efficacy and safety of volanes...
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IONIS Investigative Site
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A Study to Evaluate the Effect of Volanesorsen on Cardiac Repolarization Conducted in Healthy Volunteers PHASE1 The primary objective of this study is to assess the corrected QT interval ...
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The Approach Open Label Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants With Familial Chylomicronemia Syndrome PHASE3 An open-label study of volanesorsen (ISIS 304801) administered subcutaneous...
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IONIS Investigative Site
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A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRX) Administered to Adults With Familial Chylomicronemia Syndrome (FCS) Previously Treated With Volanesorsen PHASE3 The purpose of the study is to evaluate the safety, tolerability, pharmacok...
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Active Not Recruiting
Location
Diabetes/Lipid Management & Research Center
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Safety, Tolerability, and Pharmacokinetic Study of ISIS ApoC-III Rx in Hypertriglyceridemia PHASE2 The purpose of this study is to evaluate the dose/response pharmacodynamic ...
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Farmville Internal Medicine
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